The article highlights the history of the Department of Epizootology and Organization of Veterinary Affairs of the Moscow State Academy of Veterinary Medicine and Biotechnology – MBA named after K. I. Scriabin from the date of its foundation to the present. The heads are presented with an indication of their contribution to the development of veterinary science, practice and veterinary education in our country. The main achievements and scientific and practical developments of the staff of the department in different time periods are reflected, information about the methodological and scientific base is given. The path of development of the scientific school of epizootologists, founded by an outstanding infectious disease scientist, a full member of the Academy of Sciences of the BSSR, honorary academician of the VASHNIL, laureate of the State Prize, Professor Sergey Nikolaevich Vyshelessky, is traced.

A review of the literature on the topic of specific prevention of infectious rhinotracheitis in cattle is presented. Various approaches to prevention are considered: the use of different types of vaccines, the use of vaccine prophylaxis with immunomodulators, an approach to general prevention with the content of calves in individual houses, the influence of the method of administration of vaccines, a comparison of the administration of different types of vaccines, various purposes of vaccine administration, the use of means of nonspecific prevention, also a comparison of vaccination applications in accordance with the instructions and with departure from it, comparison of vaccination of healthy animals and animals infected with various viruses.

Adenoviruses are a group of viral pathogens that are commonly found in various vertebrates. The systematics of these viruses is based on the features of their biology and similarities in the organization of the genome. Representatives of the genera Mastadenovirus and Atadenovirus are pathogens of various ungulates, occurring in cattle and sheep, as well as in various deer species. The article presents the results of screening PCR studies aimed at detecting adenoviruses in biological material from wild mooses and roe deer shot in the Moscow region during the winter hunting seasons of 2019–2021. During PCR with electrophoretic detection of amplification products, primers were used for different parts of the adenovirus genome. Primers for amplification of the E2A fragment of the adenovirus genome made it possible to detect adenovirus DNA in the material from roe deer. The phylogenetic analysis of the nucleotide sequence confirmed that the virus belongs to adenoviruses and made it possible to attribute the detected pathogen to the genus Mastadenovirus. The phylogenetic tree showed the relationship of the detected virus with adenovirus of cattle type 3, mastadenoviruses of the white-tailed and northern salts. It is assumed that the roe deer is the owner of its own species of adenovirus. The features of diseases caused by mastadenoviruses and the problems associated with obtaining information about the complete genome and biological properties of the virus are discussed.

The article presents materials on the evaluation of the epizootic situation of necrobacteriosis in industrial farms of various types of cattle management and in the small individual farms of the Kaliningrad region, taking into account natural, geographical and climatic features, and also analyzes the effectiveness of various methods for the prevention and treatment of this diseases in the farms of the region.

The scientific article presents generalized results of laboratory studies on brucellosis of animals in order to study the epizootic situation and identify the main causes of epizootic outbreaks in Russia for the period from 2019 to 2021. The data source is the materials of annual reports submitted by the state veterinary laboratories of the subjects of the Russian Federation on the reporting form 4-vet, other official statistical data of the veterinary and medical services of the country. In the Russian Federation, new epizootic foci of brucellosis are detected annually. Different animal populations (cattle, small cattle, pigs, reindeer, dogs) are involved in the epizootic process of brucellosis. So, for the period from 2010 to 2020, 4,283 unfavorable points for brucellosis of cattle were identified in the country, 398 for brucellosis of small cattle, which contained 95 979 and 15 880 heads of sick animals, respectively. According to the results of laboratory diagnostics of brucellosis of animals by bacteriological methods performed by state veterinary laboratories of the subjects of the Russian Federation for the period from 2019 to 2021, the culture of the causative agent of the disease was isolated in 44 cases. When conducting mass lifetime studies by serological methods, animals that respond positively to brucellosis are detected annually, from 7920 to 13 059 individuals. The main causes of epizootic outbreaks of brucellosis of animals: incomplete and untimely identification of sick individuals; violation of the deadline for slaughtering positively reacting to brucellosis and sick animals (overexposure in the farm); non-compliance by business entities with the requirements of Veterinary rules on brucellosis of animals; concealment by animal owners from the state veterinary service of the true number of livestock, which does not allow to cover all animals specific vaccination and diagnostic tests. It can be concluded that the epizootic situation of brucellosis remains quite tense on the territory of the Russian Federation. Untimely and incomplete detection of the causative agent of the disease is the cause of infection of animals and causes a long course in disadvantaged areas.