Introduction: Venous thromboembolism (VTE) is a leading cause of postoperative morbidity. In hospitalized patients, it is a common and potentially fatal complication. Knowledge, positive attitude, and effective practice on VTE prophylaxis are vital for the proper management of patients. Inadequate knowledge and poor practice of health professionals towards VTE prophylaxis increased patients’ complications. Objective: To assess knowledge, Attitude, practices, and associated factors towards VTE prophylaxis among health professionals for adults hospitalized patients at the University of X in 2021. Methods: A hospital-based cross-sectional study on 404 health professionals from May, 10 to June 20, 2021, at University of X hospital. Consecutive sampling was used to select the study participants. Both bivariable and multivariable logistic regressions were used to identify factors associated with the knowledge, attitude, and practice level of health professionals towards VTE prophylaxis. In multivariable analysis, variables with a p-value of <0.05 were considered statistically significant. Hosmer-Lemeshow test was used to check for model goodness-of-fit. Results: A total of 404 health professionals who worked at the University of X hospital involved in the study with a response rate of 96%. The overall proportion of satisfactory knowledge, positive attitude, and good practice towards VTE prophylaxis for hospitalized patients were 49.8% (95% CI: 44.8–54.7), 87.1% (95% CI: 83.85–90.41), and 39.9% (95% CI: 35.1–44.6) respectively. Health professionals whose years of experience >10 years were greater than 5 times (AOR = 5.415, 95% CI 1.037–28.287) more likely to have satisfactory knowledge about VTE prophylaxis as compared to professionals who had less than 5 years of experience. Experience, work unit, knowledge, and level of education were associated significantly with practice. Conclusion: and recommendations: A low degree of knowledge and poor practices on VTE prophylaxis among health professionals noted in this study. We recommend to implement local guidelines and policy. Highlights

Background: Venous thromboembolism (VTE) is a condition in which blood clots develop in the deep veins, especially in the lower limb veins. Intensive care unit (ICU) patients have a greater risk of thrombotic events due to additional risk factors such as immobilization, mechanical ventilation, and central catheters. In medical-surgical critically ill patients, the occurrence of symptomatic or asymptomatic DVT without thromboprophylaxis is 13–31%. Objective: To assess the practice of venous thromboembolism prophylaxis in medical-surgical adult ICU. Methods: All consecutive critically ill patients in ICU from January 10, 2021, to Jun 9, 2021, were included in the study. Data were collected using reviewing the patient chart and interviewing the responsible body in ICU including the residents and nurses. The same patient was not included twice within the same cycle, or in the second cycle, if he/she was still in the ICU at the time of the second cycle excluded by observing previous patient ID. The data was processed and analyzed by using SPSS version 20 and Microsoft Excel 2010. Result: A total of 90 surgical-medical ICU patients were observed. All of the patients in the sample were receiving some form of VTE prophylaxis (100%), but none of them (0%) had the risk stratification documented in the chart. Conclusion: and recommendations: It's critical to emphasize the importance of VTE risk stratification documentation in patients' charts. We recommend that the ICU staffs to follow a specific protocol for VTE risk stratification and prophylaxis dosing based on well-known guidelines and recommendations and that once that protocol is implemented, an awareness and education campaign be applied. Highlights