We found an association between a common variant in a gene at 19q and isolated clefting in two heterogeneous populations. However, it is unclear from our data if rare variants in PVR and PVRL2 are sufficient to cause clefting in isolation.

Summary: Three cases of heterotopic ossification in abdominal scars are presented. The aetiology and pathogenesis of this condition are discussed with reference to the literature. Awareness of its occurrence will prevent anxiety and unnecessary investigations. When symptomatic, the treatment is local excision with or without local irradiation. IntroductionOssification in scars is apparently encountered only occasionally, and accounts of this in the British literature are few. We report three cases treated in our department recently.