Main feature of modern mining dump trucks is the need to ensure the transportation of minerals with minimal costs, which is achieved by deepening the quarries (in order to save overburden), increasing the slopes of roads, reducing the distance of cargo transportation, increasing the load capacity of machines and improving the safety of their movement. It is shown that new work conditions of dump trucks and major specific requirements are resolved mainly at the stage of layout of machines by optimizing wheel arrangement of dump trucks, loading of tires and their performance, providing specific power of the propulsion system, choice of the transmission type and its units, and major systems to ensure operational safety: brakes, steering, stability of motion. Special attention is paid to the creation of a new system for improving lateral stability and its design for dump trucks with a load capacity of more than 400 t. The results of operational studies of the main layout and design solutions adopted for a dump truck with a load capacity of 450 t are presented. Efficiency of the decisions made is shown which made it possible to create a mining dump truck superior to all analogues in the world by indicators of the main operational properties that ensure competitiveness: fuel efficiency, performance, and operating costs. A system created for the first time for increasing lateral stability (schematic diagram and structural elements) confirmed the projected traffic safety in typical quarries and the necessary life in operation.