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In this work, we demonstrate the results of measuring the optical properties of rat liver tissue slices after the liver itself underwent the perfusion procedure with an isotonic solution. The approach is suggested as a means to attenuate the influence of blood absorption on recorded characteristics and demonstrates its effectiveness in changing the composition of recorded spectra in the visible range. The data obtained seem promising to be used to upgrade the proposed methodology and apply the results for the diagnosis and modeling of light-tissue interaction in liver under healthy and pathological conditions.

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