The detection of basic calcium phosphate (BCP) crystals in the synovial fluid of patients with osteoarthritis is important as they represent a therapeutic target as well as a potential biomarker for the disease. This review collates the work that has been done on developing analytical assays for BCP crystals.

A novel, multimicrocapillary flow reactor (MμCFR) was constructed and applied to a series of sensitized photoadditions involving 2(5H)-furanones. The reactor allowed for rapid and energy-, time-, and space-efficient sensitizer screening, process optimization, validation, scale-up, and library synthesis.