No abstract

The present study looks at serum concentration levels of myeloperoxidase (MPO) and high-sensibility C Reactive Protein (hs-PCR) concentrations in 91 patients who presented thoracic pain localised on the sub-clavicular left side, which bothered them several times a day, where an episode lasted up to 30 minutes. Additional preclinical investigations revealed normal resting state/effort electrocardiograms, and the cardiac ultrasound revealed a diastolic cardiac dysfunction with a conserved ejection fraction. The conclusion of our study is that undertaking the exploratory tetrad (electrocardiogram, echocardiogram, serum dosage of MPO and hs-PCR) in patients who present anterior left pain, regardless of the degree of intensity, allows stratifying risks, at least through early detection of an existent diastolic cardiac dysfunction with conserved ejection fraction, which recommends changes in diet and lifestyle along with therapy.

No abstract

The study is motivated by the existence of a still controversial etiopathogen on Burning Mouth Syndrome. The objective of the study, which is carried out on a group of 103 sick of both sexes, presenting the Burning Mouth Disorder - the primary form, is to identify the prevalence of the disease and establish possible correlations with coexistence of age, gender and dyslipidemia as factors that can be considered as favoring the installation non-specific oral allergy. The conclusions of the research constitute an argument for admitting the hypothesis of the existence of a neuronal irrigation deficiency, manifested both at the conductive sensory fibers of the influx and, more preferably, at the sensory-sensorial cortex for pain and taste, or only at one of these levels. According to the hypothesis, neuronal suffering consists in a deficiency of energy production and use, induced by excessively local reactive oxygen species, through irrigation, developed by the presence of arteriosclerosis.

The justification for choosing and this enzyme marker to investigate the variation in serum concentration is supported by at least two arguments: cytokine myeloperoxidase at the level of the hypocritical myocardium, with or without contractile deficiency, can be secreted by any type of component or resident in the myocardium In cardiac failure, one of the forms that responds to the oxidative stress existing in the disease is MPO secretion that occurs early after some authors even during Class I contractile myocardial deficiency (NYHA classification).