The method of quantum-chemical modeling investigates intermolecular interactions between epoxyamine grid and hydroxides of metals of various chemical nature. It was established that the influence of hydroxide on the structure and spatial conformation of the grid depends on the acid-base properties and increases with increasing alkalinity of the hydroxide. It is shown that for certain an alkaline property of hydroxide, due to strong intermolecular interactions, the spatial conformation of the grid is significantly changed.