Lack of access to affordable, accessible, over-the-counter medications and health-related items affects school attendance, academic performance, and individual health. Increasing access through innovations, such as Pharmacy Vending Machines (PhVMs), may address the burdens students face in university settings. In January 2021, two PhVMs were placed on Purdue University’s campus to increase access to affordable and dependable 24/7 family planning items, cold/flu remedies, and other popular over-the-counter pharmaceuticals. Based on the success of the initiative and growing student body, the program was expanded to include two additional machines in August 2021. In this article, we detail how Purdue University planned, implemented, and evaluated a campus-wide PhVM program, which was an interdisciplinary collaboration across students, faculty, and staff in the College of Health and Human Sciences and College of Pharmacy. Pharmaceutical product availability in convenient vending machines dispersed throughout a campus contributes to a solution for the increasing demand for health products among consumers in large geographic areas.