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The amount of forming pinocytic (coated) microvesicles on the apical plasma membrane of kidney proximal tubule cells was assessed in kidney biopsies of 10 patients suffering from chronic glomerulonephritis. A significant correlation was found between the amount of these vesicles and diurnal proteinuria levels (r =0.889; p < 0.01). The possible mechanisms of protein reabsorption via pinocytosis in both normal and pathological conditions are considered.

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