The use of high-strength sandy concrete (HSSC) is an alternative to high-strength crushed stone. Its use is profitable for those regions of Russia in which crushed stone is an imported building material. Thus, crushed stone is supplied to the Republic of Tatarstan (RT) from the Ural, and the local reserves of sand are significant. Authors presented the results of studies to determine the economic efficiency of solid columns’ erection in one-story industrial buildings with bridge cranes according to the 1.424.1-5 series from HSSC of HSSC60 and HSSC80 classes in comparison with heavy concrete of B20...B80 classes. Studies have shown that in relation to Kazan, the use of HSSC of HSSC60 and HSSC80 classes in comparison with heavy concrete of B20...B40 classes, depending on the size of the span, column spacing, floor height and lifting capacity of cranes, can reduce steel consumption by 43.2…71.5 %. At the same time, the total cost of materials (steel and concrete) when using heavy concrete of B20...B40 classes is 1.7 %...38.1 % lower than with HSSC60 and HSSC80. This is due to the sharp rise in the cost of concrete in the Russian market in the third quarter of 2002 and continuing to the present (second quarter of 2021). When recalculated before the indicated price increase, the use of HSSC60 and HSSC80 in comparison with heavy concrete of B20…B40 classes gives a decrease in the total cost of materials by 1.9...34.5 %. The results obtained are novel because in the scientific and technical literature there is no information about the design of these columns from the HSSC.