The results of immunoglobulin typing of 278 Tuvinians for Glm (f, z, a, and x), G3m (b, 0, 1, 3, 5, c3, 5, g, s, t and v), A2m (1 and 2) and Km (1) indicate these southern Siberians to have the Caucasian haplotype Gm^f;b Am¹ (0.100), the Oriental haplotypes Gm^f;a;b Am¹ (0.022), Gm^{f, a;b}Am²(0.040), Gm^{z, a;b, s, t}Am¹ (0.027) and Gm^{z, a;b, s, t}Am² (0.107). The haplotypes distribution for Gm^z;a;gAm¹ (0.279), Gm^{z, a}; sAm²(0.065), Cm^{7, a}; ^χ. sAm¹(0.101) and Gm^{z, a,x;g}Am²(0.030) are similar to those found in oriental populations. The striking feature of this population is the presence of Gm^{z, a;b} Am¹ (0.108) and Gm^{z, a;b} Am² (0.122) previously thought to be characteristic of African or Papuan populations, indicating that a third focus of the Gm^{z, a;b} haplotypes exists in Central Asia. The Km¹frequency observed (0.125) is intermediate between Caucasian and previously studied northern Oriental populations.