CACGTCCCAACGCTACATC, ACGTGCCCACCCAGATCAAAA; 36b4 AGTACACCTTCCCACTTACTG, ACCAAGTCAAGAGACT-GTCTC; Tbp ACCCTTCACCAATGACTCCTATG, ATGATGACTG-CAGCAAATCGC. Statistics. The observed birth rate of Lpin2/3-KO mice was compared with the expected number (according to Mendelian inheritance) by χ 2 test. Quantitative results are presented as mean ± SD. Two-way ANOVA or 1-way ANOVA, followed by Bonferroni's correction was used for multiple comparisons (Stata 11). A value of P < 0.05 was considered statistically significant. Study approval. The Institutional Animal Care and Use Committee of UCLA approved all animal experimental protocols.

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