2-tailed Student's t test or log-rank test. P < 0.05 was considered significant. Serial glucose and GTT for streptozotocin-treated WT and knockout mice ( Figure 7) were compared using multiple unpaired t tests and corrected for multiple comparisons using the Šidák-Bonferroni method, with α of 0.05.Study approval. Animal studies were approved by the Institutional Animal Care and Use Committee
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