The incidences of infectious and noninfectious endophthalmitis after IVT were low, and the risk did not increase with each successive injection. We found higher rates of noninfectious endophthalmitis with bevacizumab compared with ranibizumab or aflibercept. Three quarters of cases with infectious and two thirds of cases with noninfectious endophthalmitis retained vision within 10 letters of the pre-endophthalmitis level.

A match made clear The fabrication of strong and tough composites is of interest in many technologies, such as the combination of mechanical performance with transparency for robust display systems. Amini et al . combined and centrifuged glass flakes with poly(methyl methacrylate) (PMMA) to make a transparent composite. By doping the glass flakes, it was possible to alter the refractive index of PMMA to maximize optical clarity. Such composites show good strength and toughness and could have a wide range of potential applications as an alternative to current glass composites. —MSL

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Laser interferometry appears to be a feasible and satisfactorily accurate method to calculate IOL power in some silicone oil-filled eyes. Further studies comparing this technique to others are warranted.

PURPOSE: To report the characteristics and incidence of rhegmatogenous retinal detachment in myopic eyes after LASIK. METHODS: The medical records of 49 patients with rhegmatogenous retinal detachment after LASIK were reviewed. The incidence of rhegmatogenous retinal detachment after LASIK was determined and potential risk factors were evaluated. RESULTS: LASIK was performed on 59,424 eyes with spherical equivalent refraction (SE) ranging from -0.75 to -26.50 diopters (D) (mean: -6.10 ± 3.5 D). Forty-nine eyes developed rhegmatogenous retinal detachment between 1.5 and 76 months (mean: 27.3 ± 21.7 months) after LASIK. The mean preoperative refractive error in these eyes was -8. 6 ± 3.9 D. Mean age of these patients was 38.2 ± 11.2 years. Thirty-five (71.4%) patients were male. The cumulative incidence of rhegmatogenous retinal detachment was 0.082% (95% confidence interval [CI]: 0.061-0.109), and the yearly incidence was 0.032% (95% CI: 0.023-0.042) after LASIK. The most frequent location of the retinal breaks was the superior temporal quadrant (22.7%). Male sex, older age, and higher preoperative myopia were significantly related to the incidence of rhegmatogenous retinal detachment after LASIK (P<.001). CONCLUSIONS: Based on the results of this study, following the treatment of high-risk peripheral retinal lesions, LASIK did not appear to be an additional risk factor for the development of rhegmatogenous retinal detachment after LASIK in our patients; however, patients should be informed of the possibility of this complication as a consequence of myopia. Patients who are male, older in age, and have high myopia preoperatively may be at increased risk. [J Refract Surg. 2006;22:448-452.]