In the recent years scientific and technological advancements have been made in the research and development of oral drug delivery systems. The aim of this study was to formulate and evaluate of orodispersible tablets by direct compression for fenofibrate by using super fast disintegrating agents like croscarmellose sodium. The use of super disintegrant and excipient for preparation of fast disintegrating is highly effective and commercially feasible. In the present investigation poorly water soluble drug is one of the most important parameters of oral formulations sucessfully developed fenofibrate was using solvent evaporation method drug: PEG 6000 in (1:5 w/w). The formulation F7 was the optimized formula that showed satisfactory results with various physicochemical evaluation parameters like thickness, hardness, weight variation, friability, drug content, % drug release almost 79.98% within 15 min. and it was follow the maximum higuchi release kinetics that regression coefficient values ‘r2’= 0.995.
The herbal cosmetics are natural and free from all the harmful synthetic chemicals which generally may turn out to be lethal to the skin, the natural ingredient used assures no side effect one can applied them any time. So, herbal cosmetic are more referable as compared to synthetics one.The purpose of the present work is to formulate and evaluated herbal hand wash using natural ingredients to promote the personal hygiene. The formulated hand wash was evaluated for different parameters like pH, colors, foaming efficiency, viscosity and stability. The herbal hand wash formulated using neem extract for antibacterial property, aloevera juice for soothing property, glycerine for moisturization, sodium lauryl sulphate as a surfactant, carbopol 934 as a jellying agent, rose oil for fragrance and distilled water, the hand wash is prepared and evaluated then the result was documented. 5 People were asked for acceptability of fragrance and their opinion was taken. The fragrance was found to be good as compared to reference hand wash.: The hand wash was found to be light green aromatic and homogeneous with rosy fragrance. pH was 6.0 which is similar to the skin pH. The hand wash was found to be stable in all evaluation parameters with good cleaning property.
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