The presence of homozygote polymorphic variant of BclI might be good predictive markers for the disease susceptibility. The BclI and the TthIII1 polymorphism are associated with sex-specific clinical parameters. Our findings also suggest that the combination of BclI and TthIII1 polymorphisms may play a protective role in blood glucose.

No abstract

No abstract

Resource allocation is an important problem for cloud environments. This paper introduces an energyaware combinatorial auction-based model for the resource allocation problem in clouds. The proposed model allows users of a cloud to submit their virtual resource requests as bids using the provided bidding language which allows complementarities and substitutabilities among those resources to be declared. The model finds the most profitable mutually satisfiable set of winning bids, and the corresponding allocation of virtual resources to the users while considering the placement of virtual resources to the available physical resources in the cloud by executing an optimization problem. During the optimization, the model also takes account of the non-linear energy requirements of the physical resources based on their utilization levels to find a placement with the lowest energy cost, thus, providing an energy-aware solution to the resource allocation problem. The associated optimization problem is formally defined and formulated using integer programming. Since the optimization problem is intractable, four heuristic methods are also proposed. To evaluate the performance of the model and the proposed heuristic methods, several experiments are conducted on a comprehensive test suite. The results demonstrate the benefits of the proposed model, and the high-quality solutions provided by the proposed methods.

No abstract