BackgroundThe aims of this retrospective study were to evaluate the maternal and prenatal outcomes between 35 years and older pregnancies and younger pregnancies, and the effects of the age of pregnancy, mother and newborn.MethodsPregnant women who gave birth in Vakif Gureba Training and Research Hospital, Clinic of Obstetrics and Gynecology in 2006 were retrospectively screened. Pregnant women aged 35 years and over were included in this study and the pregnant women between age range of 30 - 34 years were included in the control group.ResultsPregnancy rate was found as 7.1% in 35 years and older women in all the deliveries, cesarean delivery rate was found as 46.1% in this group at 1 year period. However, cesarean delivery rate was 40.9% in the control group. Cesarean delivery rate was found as 31.6% in all the deliveries. The most common cause of cesarean section indication was fetal distress in advanced maternal age (AMA) (11.7%), whereas previous cesarean section was found as the most common cause in the control group (15.1%).ConclusionNo significant difference was found between AMA group and normal pregnancies in terms of preterm labor, caesarian section, morbidity, mortality and chronic diseases such as hypertension and diabetes mellitus.

Background: We aimed to reveal how chronic diseases, age and gender affected morbidity and mortality in patients with Coronavirus disease of 2019 (COVID-19). Methods: Medical records of all reverse transcription polymerase chain reaction (RT-PCR) positive COVID-19 patients followed up in hospital and home isolation between 13th of Mar 2020 and 12th of May 2020 were retrospectively reviewed. The patients were from Kayseri Province, Turkey. Patients’ demographic and clinical characteristics and the factors associated with morbidity and mortality were analyzed. Results: Of all the patients, 773 (95.8%) were alive and 34 (4.24%) died. The fatality rate was 4.2%. There were differences between the age groups in terms of fatality rate (P<0.001). The fatality rate in patients above the age of 65 yr was significantly higher. The fatality rate in the male gender was 2.44 times higher (P<0.05). It was 1.104 times higher in advanced age (P<0.001) and 10.893 times higher in patients with at least one comorbid disease (P<0.05). Hypertension increased mortality by 3.635 times (P<0.05) and chronic pulmonary diseases by 2.926 times (P<0.05). Conclusion: Advanced age, male gender and accompanying chronic diseases have adverse effects on the course and severity of the disease and hospitalization. They also increased the rate and risk of mortality.

BackgroundWithin the context of the support program for smoking cessation, initiated by the Turkish Ministry of Health in 2011, those who present at ‘smoking cessation’ centres and are found to be suitable for pharmacological treatment are given varenicline and bupropion free of charge. As the smoking cessation programme is centralized, the selection of the medication is made randomly to provide a fixed distribution rate. The aim of this study was to evaluate the efficacy of both varenicline and bupropion in smoking cessation and to evaluate the effect of the smoking cessation programme.MethodsA total of 405 individuals who met the study criteria were included in the study. Smoking habits and degree of dependence were determined in all the participants with the Fagerstrom test for nicotine dependence (FTND) and bupropion or varenicline therapy was initiated in those who were eligible. Patients were followed up at 15 days then at 1, 2, 3, 6 and 12 months after smoking cessation. A level of CO < 5 ppm and ‘point prevalence abstinence’ were used as the criteria of success for smoking cessation and this evaluation showed the non-smoking status in the previous 7 days.ResultsThe mean age of the participants was 35.19 ± 7.73 years and 82.8% (n = 334) were male. Of the participants, 60.2% (n = 244) were given varenicline and 39.8% (n = 161) bupropion. The mean FTND and package/year was not significantly different between the groups. The rates of success in the 1st and 2nd weeks, and 1st, 3rd and 6th months were significantly higher in the varenicline group than in the bupropion group (p < 0.05). At the end of one year, the rate of smoking cessation was determined as 13.9% (n = 34) in the varenicline group and 6.2% (n = 10) in the bupropion gruop. The difference was statistically significant (p = 0.015). At the end of 1 year when the previous 7 days smoking status was evaluated with the ‘point prevalence abstinence’ measurement as the success criteria, success rates were 20.5% with varenicline and 18.6% with bupropion and the difference was not significant (p = 0.646). The individuals who used the medications for 45 days or longer were more successful in smoking cessation (p < 0.001). The most common reasons given for discontinuing the medication were the side-effects (31.5%). No significant difference was determined between the groups in respect of the side-effects observed.ConclusionsAlthough the rates of smoking cessation in all the other control points were higher with varenicline than with bupropion, no significant difference was found between the success rates of varenicline and bupropion used in smoking cessation based on the last 7 days at the end of one year. Those who used the medications for 45 days or longer were more successful in smoking cessation.

ÖZET Amaç: Hastanemiz sağlık kuruluna başvuran hastaların, başvuru nedenleri, engellilik oranları ve bunların yaşlara göre dağılımını inceleyerek ülkemizdeki engelliler ile ilgili epidemiyolojik bilgiye katkı sağlamaktır. Yöntem: Ocak 2014-Aralık 2014 tarihleri arasında Karabük Üniversitesi Eğitim Araştırma Hastanesi sağlık kuruluna başvuran hastaların kayıtları retrospektif olarak incelendi. Sonuçlar oransal olarak tanımlandı. Bulgular: Hastanemiz engelli sağlık kuruluna Ocak 2014-Aralık 2014 arasında 2637 olgu başvurmuştur. Bu hastaların 1554'ü erkek (%58.9), 1083'ü kadın (%41) idi. Yaş arttıkça başvuru sıklığı artmıştır. En fazla başvuru 65 yaş üzeri grupta olmuştur. Hastalar sağlık kuruluna en sık engellilik tespiti nedeniyle, 2. sıklıkla özel eğitim alabilmek için başvurmuşlardır. Engellilik oranı %40 ve üzerinde olanlar engelli haklarından yararlanmaktadır. Buna göre %40'ın üzerinde puan alan olgu sayısı 1834'tür (%69.5). Bunların 1055'i erkek (%40), 779'u kadındır (%29.5). İncelenen olgulardan 569 kişi (%21.5) ağır engelli idi. Ağır engelli olanların 317'si kadın (%12), 252'si erkekti (%9). Sürekli engelli oranına sahip olgu sayısı 1638'dir (%62). Bunların 960'ı erkek (%36), 678'i kadındır (%26). Hastaların branşlara göre dağılımı değerlendirildiğinde en sık 976 (%37) olgu ile ortopedi ve fizik tedavi uzmanları tarafından yapılan kas iskelet sistemi hastalıkları tespit edilmiştir. En az özür oranı ise 8 (%0.3) olgu ile kadın hastalıkları branşından olmuştur. Sonuç: Engelli nüfusun yaşam kalitesi ve onlara sunulan hizmetin kalitesi, toplumun gelişmişlik düzeyi ile yakından alakalıdır. Engelli bireylerin hayat kalitesini düzeltebilmek için öncelikle bölgesel olarak ve ülke genelinde bu bireylerin verilerine ihtiyaç bulunmaktadır.ABSTRACT Aim: Disabled patients are admitted to the medical board to determine the disability rate in order to use the occupational, health and social rights in Turkey. According to the law, over 40% of individuals with disabilities, based on the severity of their disability and illness rate, have different rights. We aimed to contribute to epidemiological data on people with disabilities in our city. cases were evaluated. 1554 of these patients were male (58.9%), 1083 women (41%). With the increase of age, the frequency of application increased, too. Maximum application was in the group who are above 65 years of age. The numbers of cases by over 40% points are 1834 people (69.5%).1055 of them were men (40%), 779 were women (29.5%). When the cases were evaluated according to the distribution of branches, 976 cases (37%) in musculoskeletal system were identified. The least disability was in Obstetrics and Gynecology with 8 cases (0.3%). Conclusion: Quality of life of the disabled population and the quality of services which are offered to them are closely related to the level of development of the society. In order to improve the life quality of disabled people, regional and country wide data of these people are needed.

Objectives: Comorbidities represent a risk factor for adverse events in several critical illnesses. The aim of this study was to identify the relationship between the Charlson Comorbidity Index (CCI) with mortality and length of stay (LOS) in critically ill elderly patients. Methods: A retrospective analysis was made of patients admitted to our tertiary adult intensive care unit (ICU) between January 2015 and January 2016. The impact of comorbidity was evaluated with the CCI. Other required data were retrieved from the patients' follow-up records. Results: The study included a total of 251 patients. The mean age was 78.79 ± 6.70 years. The total mortality rate was 41.0%. The most common cause for admission was sepsis and acute respiratory failure (18.3% vs 18.3%). The median APACHE II score was significantly higher in non-survivors than survivors (31.