It is likely that radiosensitive patients have less efficient mechanisms of elimination of apoptotic cells with DNA damage resulting in accumulation of LAN cells and facilitating adverse reactions. Our data suggested that the grade of adverse reaction may positively correlate with LAN cells in PBL before and during radiotherapy.

The paper deals with a systematic approach to education as well as to other areas, which represents a tool ensuring that education was performed effectively and efficiently, that it had positive influence on the society and the individual and it had improved their job performance and quality of life. This rational approach to the development of educational programs, their execution and quality evaluation enables to reach strategic education aims successfully and in a way that they suit and stimulate the requirements of practice.