Presently, population ageing is one of the main demographic trends in developed countries, including Russia. The article analyzes changes in life satisfaction of individuals aged 45–72 and reflects the main factors influencing this indicator. The research method employed in the study is econometric analysis based on data of the 21st, 23rd, 25th and 27th rounds of the annual Russian Longitudinal Monitoring Survey – Higher School of Economics (RLMS-HSE). The analysis showed that such indicators as self-assessment of health, income, having a pension and a permanent marital partner had a significant positive impact on life satisfaction for older individuals. It has been revealed that for both sexes an important factor of life satisfaction is the employment status, while the kind of activity turned out to be not statistically significant. The family status and family composition do not have any significant impact on life satisfaction for men, but they do for women.