Staphylococcus aureus is a pathogen associated a different kind of infection. Molecular markers are useful tools to study microbial epidemiology. Twenty two methicillin-resistant S. aureus (MRSA) and 23 methicillin-susceptible S. aureus (MSSA) were studied by mecA gene, SCCmec cassette, Panton Valentine leucocidin (PVL) and spa polymorphism. The clinical data patients were analyzed. MSSA was prevalent in samples different from skin and soft tissue (SST) and in hospitalized patients, whereas MRSA in SST. SCCmec type IV was predominant, followed by type I. Low presence of PVL was found. In MRSA 11 different types of spa were detected, t019 was the most frequent and associated with outpatient, 17 types were found in MSSA and t189 was prevalent. spa t002 was present in MSSA and MRSA. We found 11 types of spa not reported in our country.
Body piercing is a type of self-expression which is based on creating a hole in the skin, subcutaneous tissue or cartilage in order to be able to insert jewellery. The aim was to report severe CA-MRSA infections in two patients, one adult and one child, from different teaching hospitals, in the same period of time and both of them had penetrating implantation as a risk factor. The two isolates were CA-MRSA PVL (+), spa t019, cassette IV and ST30.Referring to the clonal relationship, PFGE showed that both isolates were closely related, indicating that they were probably part of the outbreak. It was not possible to investigate if the piercing setter was the same person in both cases. Mutlu B. Comparison of risk-taking behaviour and frequency of piercing and tattooing among university students. JPak Med Assoc. 2015;65(6):587-592. 3. Purim KSM, Rosario BA, Rosario CS, Guimarães ATB. Piercings in medical students and their effects on the skin. An Bras Dermatol. 2014;89(6):905-910. Méndez EA, et al. J Bacteriol Parasitol, Vol.10 Iss.2 No:356 18. Tenover FC, Arbeit RD, Goering RV, Mickelsen PA, Murray BE, Persing DH, et al. Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J Clin Microbiol 1995;33(9):2233-2239. Méndez EA, et al.
Aggregatibacter actinomycetemcomitans es una bacteria Gram negativa que se encuentra formando parte de la microbiota normal de la cavidad oral en el hombre. Cuando existe un estado de inmunidad deprimida en el huésped, este microorganismo puede ocasionar cuadros infecciosos, entre ellos endocarditis. La endocarditis infecciosa (EI) es una enfermedad poco frecuente y grave, en particular si el agente causal es un microorganismo fastidioso, cuya identificación puede retrasarse. El diagnóstico precoz de la enfermedad, la identificación temprana de los pacientes con más riesgo, así como un abordaje multidisciplinar pueden ser estrategias válidas para mejorar el pronóstico de estos enfermos. Reportamos el primer caso en Santa Fe de EI en paciente con inmunodeficiencia adquirida (VIH), sin antecedentes de cardiopatía. El tratamiento con ceftriaxona resultó eficiente y el paciente no requirió intervención quirúrgica.
Staphylococcus aureus es uno de los patógenos más importantes para el humano, por su virulencia y capacidad de adquirir rápidamente resistencia a los antimicrobianos, es responsable de infecciones diversas, tanto de origen comunitario como hospitalario. Las Infecciones por Staphylococcus aureus resistente a la meticilina circunscribían hasta hace no demasiado tiempo exclusivamente al ámbito hospitalario (SARM-AH) y desde la década de los 90’ un problema también frecuente en la Comunidad (SARM-AC), en pacientes previamente sanos. En la actualidad, las cepas SARM-AC que son genéticamente diferentes a las SAMR-AH, son responsables de las infecciones asociadas al cuidado de la Salud. Presentamos el caso clínico de una infección invasiva por SARM-AC en un niño prematuro y su madre. Los aislamientos portaron el gen mecA, la leucocidina de Panton-Valentine, el cassette SCCmec tipo IV y spa t019 (por asociación: ST30). Ambos aislamientos, atendiendo a criterios fenotípicos y moleculares, fueron categorizados como SARM-AC.
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