Fast speed of the communication integration and information transmittal has caused something called information and communication technology (ICT).Because it is the first experience of e-services through rural ICT centers in Iran, different studies and investigations are needed to identify and apply the proper applications related to the village. This study is aimed at evaluating the factors affecting the villagers' use of rural telecentres from 2010 to 2011. This is applied study and the methodology is descriptive co relational. The main tool of the study is questionnaire. Statistical population of the study was 190686 villagers of Hamadan, Razan, and Asad Abad cities from which 230 ones were selected by proportional stratified sampling method. After data extraction, SPSS version 17 was used in the statistical analysis. Findings showed that most of the villagers' use of rural telecentres is little (38.3%), and their use of this kind of services was mostly related to post bank (2.75), computer and administrative services (2.31) and direct and indirect internet services (2.24). The only and the most important variable affecting the villagers' use of rural telecentres was the social -cultural factor which explained about 27% of the rural telecentres.
Background: Some studies highlighted the role of Jujuboside A as a potent antioxidant on ischemic neurons. However, the definitive effect of this substance on the change in the expression of the neuroprotective genes has not been clearly identified. Therefore, this study aimed to investigate the effects of Jujuboside A on the expression of proliferation-inducing genes and cell count enhancement in the hippocampus after the induction of transient global ischemia/reperfusion. Materials and Methods: This experimental study was performed on 24 male Wistar rats in four groups control, ischemia, vehicle, and Jujuboside A. Three days after induction of ischemia, the hippocampus of animals was removed and isolated from brain tissue. In order to investigate the results of the intervention, the expression of nuclear factor-κB (NF-κB), nerve growth factor (NGF), and Brain-derived neurotrophic factor (BDNF) genes were determined using real-time polymerase chain reaction. Results: The results showed that NGF expression was significantly higher in the Jujuboside A group than in the ischemic group (P<0.05). Moreover, the expression of BDNF in the Jujuboside A group was increased compared to the ischemic group. However, the expression of NFκB in the Jujuboside A group was lower than that of the ischemic and control groups, but these changes were not significant (P>0.05). Conclusion: Jujuboside A can increase the expression of NGF by promoting a protective effect on the hippocampus after transient global ischemia/reperfusion.
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