Water resources in the Jijia catchment basin are limited and often polluted. The catchment basin of Jijia is situated in northeastern Romania and it crosses the Moldavian Plain on the north-west-south-east direction. The purpose of the present study is to analyze 26 physico-chemical parameters providing the annual and multiannual water quality index. Two water-sampling points were selected: Jijia-Victoria [S.1] and Jijia-Opriseni [S.2]. The high values of nitrates are caused by the use of nitrogen-based chemical fertilizers and of manure. Contamination with nitrites (N-NO2-) and nitrates (N-NO3-) of wetlands and deepwater habitats in the floodplain of Jijia is still high because of agricultural and zootechnical activities. The phosphorus within freshwater habitats is a consequence of anthropogenic pressure: improper storage of animal waste and/or use of phosphates-based fertilizers. Global water quality index (WQi) shows that both monitoring stations are included in the Medium high class.