Threonine (Thr) is one of the most limiting amino acids in functional ingredients used for diet preparation, and its deficiency can reduce fish growth. This study aimed to estimate the digestible Thr requirement in tambaqui (Colossoma macropomum) diets in the fattening stage for 60 days. Diets containing different digestible Thr concentrations (9.40, 10.30, 11.20, 12.10 and 13.00 g/kg) were analysed. The best results for growth performance, body crude protein content and body deposition occurred in fish fed with 10.30 and 11.20 g Thr kg diet −1 (p < 0.05). The dietary Thr requirement estimated based on weight gain, the feed conversion ratio and the specific growth rate was 10.64, 10.71 and 10.80 g Thr kg diet −1 respectively (p < 0.05). For body deposition, the best values of dietary Thr were between 10.40 and 10.70 g/kg (p < 0.05). Diets with higher levels of digestible Thr caused an increase in plasma cholesterol, liver glycogen levels and erythrocytes, and a decrease in hepatic aspartate aminotransferase levels and mean corpuscular volume (p < 0.05). In conclusion, tambaqui require between 10.40 and 10.80 g Thr kg diet −1 to provide better fish growth performance, body deposition and health.

Problema de pesquisa: o perfil da força de trabalho da Secretaria de Saúde Pública do Estado do Rio Grande do Norte e o déficit de servidores por cargo. Objetivo: descrever o dimensionamento da Força de Trabalho (FT) da Secretaria de Estado da Saúde Pública do Rio Grande do Norte. Método: foi realizado estudo com predomínio quantitativo, exploratório a partir de dados secundários. As fontes de dados foram os sistemas de banco de dados da Coordenadoria de Recursos Humanos da Secretaria Estadual de Saúde Pública do RN e Planilhas de déficit de servidores por cargo, analisados estatisticamente e apresentados em gráficos e tabelas. Resultados: a FT da SESAP/RN encontra-se com perfil predominantemente envelhecido, feminino, e com tempo de serviço igual ou superior a 25 anos. Constatou-se alto índice de vacâncias, principalmente por aposentadorias, que comprometem a manutenção de servidores nas escalas de plantão; a prática de desvios de função nos diferentes níveis; e elevado déficit de servidores. Com relação a ferramentas tecnológicas utilizadas como instrumento de gestão da FT, verificou-se que se mostram superficiais, desatualizadas, com informações divergentes, e que não vêm atendendo a demandas e processos, como o dimensionamento de RH, feito manualmente em planilhas de Excel, suscetível a erros. Conclusão: há necessidade de sistema de informação de dimensionamento para a coleta e visualização do quantitativo que venha a gerir e monitorar a FT da SESAP/RN.

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Darier disease (DD), also known as follicular keratosis, is a rare autosomal dominant hereditary acantholytic dermatosis caused by a mutation in the ATP2A2 gene. Skin lesions are characterized by persistent confluent papules, preferentially located on the seborrheic areas of the face, chest and back. The hands, feet and nails are also commonly affected. DD has a chronic course with frequent relapses. Their treatment is often difficult and unsatisfactory. We present the case of a 54-year-old male with a history of keratotic papules with a brownish-black color, with a foul-smelling, pruritic and ardent appearance on the back and trunk, since the age of 19, which worsen in the summer. His 27-year-old daughter has a similar picture with her skin lesions started at age of 17 in the region below the breast, back, trunk, feet and hands. After the skin biopsy, the diagnosis was confirmed and acitretin 30 mg/day was instituted. The importance of this case report is to alert health professionals that the diagnosis of DD should be considered in family members of patients, especially those in the first degree, and also in patients with follicular keratolytic dermatoses, being an important differential diagnosis of this group of patients diseases.