Shih Tzu dogs are within tear production standards of other breeds previously described. The mean CGCD found to LE was 13.64 ± 3.44, and to RE it was 13.64 ± 4.07. These values are lower than those described for other breeds.

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Estudo clínico e histológico das pálpebras e conjuntiva hígidas submetidas ao tratamento tópico com soluções anestésicas em coelhos [Clinical and

The pannus is an eye disease that affects dogs, mostly German Shepherds, characterized by progressive proliferation of fibrovascular tissue in the cornea. The pathogenesis is not yet definitively determined, but is believed to be an autoimmune condition.The diagnosis is established by clinical, cytological findings and the therapeutic response with use of anti-inflammatory and immunosuppressive topics. One must differentiate pannus from diseases such as keratoconjunctivitis sicca and other chronic keratitis, and also some corneal neoplasia. This study aimed to conduct a literature review on the pannus, addressing the clinical, epidemiological, pathophysiological and therapeutic aspects of this disease.

BackgroundIt has been proposed that sildenafil citrate can increase ocular blood flow, and that this property can be used to treat ocular disorders that involve reflex vasoconstriction. This study therefore proposes to ascertain the vasodilator effect of the drug on retrobulbar circulation in healthy rabbits. For this matter rabbits treated with sildenafil citrate or saline solution had their intraocular pressure (IOP), mean arterial pressure (MAP), ocular perfusion pressure (OPP) and color Doppler imaging of the external ophthalmic artery measured prior to treatment and on days one (moment M1), seven (when M2), fourteen (moment M3), twenty-one (moment M4), and thirty (moment M5) of treatment.ResultsThe MAP and OPP values of treated group were lower than those of control group at all times, and the mean values differed statistically at moments M1 (S = 71.52 mmHg, C = 84.76 mmHg, p = 0.0356) and M5 (S = 71.38 mmHg, C = 85.52 mmHg, p = 0.0252). The IOP and color Doppler values of the external ophthalmic artery did not differ between tested groups.ConclusionsThe dose of 10 mg of sildenafil citrate administered to healthy rabbits causes systemic vasodilation and consequently lower values of MAP and OPP. However, it does not induce changes in IOP and retrobulbar hemodynamics identifiable by color Doppler assessment of the external ophthalmic artery.