Propofol is effective and safe for procedural sedation in the ED. Propofol has a considerably shorter duration of action than midazolam, thereby shortening the period of sedation.

The audit identified a gap in documentation and/or clinical practice in advising women of childbearing age of the risk of conceiving when using oral contraceptive pill and antibiotics. Recommendations are given as to how this may be addressed.

eight control patients who developed nephropathy was 27.3 (3.7 to 51.0; P = 0.03) while glomerular filtration rate increased by 3.8 ( − 3.5 to 11.0) in the six patients treated with captopril with urinary albumin excretion > 300 mg/24 h during the treatment pause (P = 0.02 between the groups). Haemoglobin A 1c and blood pressure did not differ between the two groups at any time during the study.