Pharmacologically induced ejaculation is utilized in stallions when traditional semen collection procedures are not appropriate or not effective. Most common protocol includes oral imipramine hydrochloride, with intravenous xylazine hydrochloride given 1 - 2 hours later. Goal was to document success rate from past clinical experience (historical data) and to determine whether addition of oxytocin along with xylazine or a prostaglandin analogue prior to xylazine treatment would enhance success rate in aged stallions in a clinical setting. Semen was successfully collected in 3 of 7 aged stallions using the standard protocol. In the modified protocol, 22 times (out of 50 attempts) semen was successfully collected from 12 stallions. However, addition of oxytocin or a prostaglandin analog had a deleterious effect on passive emission of semen.