The tomato is an important fruit, both fresh and processed, for human nutrition worldwide, and plays a significant role in agriculture. Especially in the intensive agricultural system where chemical fertilizers are used, little is known the impact of chemical NPK fertilizer applications on the yield of tomato under chestnut soil conditions. The objective of this study was to investigate the effects of four types of NPK fertilizer applications (N120P90K60, N150P120K90, N180P150K120, N210P180K150) on the yield and yield parameters of 5 different tomato varieties (Ogonyok 777, Barin, Hybrid Shuruk, Hybrid SC-2121 and Hybrid Falcon) under chestnut soil conditions in in the Southeast of Kazakhstan. According to field experiment results, there were significant differences among the treatments in relation to yield and yield parameters (plant height, number of stems, number of leaves, and number of fetus after planting) of tomato varieties. In foothill zone of the southeast of Kazakhstan, Hybrid Shuruk and Hybrid SC-2121 tomato varieties significantly yielded higher than the other three varieties tested at the same time under chestnut soil conditions. And also, it was determined that the best outputs tended to be obtained with N210P180K150 fertilizer dose.