Hospitalized Children suffer pain from various hospital procedures, trauma, and other illnesses. A wide variety of tools for treating pediatric pain appropriately is beneficial i.e., play therapy, distraction, relaxation, and coping skills. Aim of the study: Assess the effectiveness of squeezing ball on pain during insertion of intravenous cannula among children. Material and method: in the present study, the researcher adopted a Quantitative Approach and Quasi-experimental research design. It was carried out on 60 hospitalized children. The non-probability purposive sampling technique was used for the selection of samples, data were collected using demographic profiles and squeezing ball was given to 30 children of the experimental group. The assessment of pain was done using FLACC Pain Scale and Wong Bakers Pain Scale. The reliability of the tool was found “r=0.8 for FLACC scale and r=1 for Wong-Baker scale. The pilot study was done on 10 children, the study was found feasible.