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This report presents physical and chemical data for northern San Francisco Bay waters. Samples were collected during the late summer and fall of 1984 during six cruises at near-two-week intervals. Bay waters were sampled at designated (historical) stations and selected salinities along the deep channel of northern San Francisco Bay. Measurements included temperature, salinity, turbidity, in vivo fluorescence, chlorophyll a., alkalinity, suspended particulate matter, dissolved organic carbon, and dissolved inorganic nutrients: nitrite, nitrate + nitrite, ammonium, dissolved silica, and ortho-phosphate. Numerical results are tabulated and methods are described.