CTFR modulator treatment for a larger proportion of PwCF. Early evidence with ivacaftor therapy found a positive impact on FEV1 decline, 2 thus, preserving higher pulmonary function for a longer time period. A population-based study found that ivacaftor seemed to decrease mortality risk and possibly reduced the need for the solid organ transplant in PwCF, 3 but this study was limited by a small
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.