Indonesia merupakan negara yang memiliki berbagai macam tanaman herbal berkhasiat obat. Salah satu jenis tanaman obat yang sering digunakan untuk pengobatan adalah rimpang kunyit. Rimpang kunyit mengandung senyawa alkaloid, tanin dan flavonoid yang telah terbukti sebagai antibakteri. Penelitian ini dilakukan secara in vitro untuk mengetahui kandungan senyawa dan aktivitas ekstrak rimpang kunyit yang dilanjutkan dengan pengujian menggunakan metode Kadar Hambat Minimum (KHM) terhadap bakteri Staphylococcus aureus. Penyarian ekstrak rimpang kunyit dilakukan dengan cara sokhletasi menggunakan pelarut etanol 96%. Pengujian aktivitas antibakteri dilakukan dengan metode difusi dengan variasi konsentrasi 45%, 55%, 65% dan 75%. Hasil penelitian ini menunjukkan bahwa ekstrak rimpang kunyit 45% merupakan konsentrasi minimum yang memiliki aktivitas antibakteri terhadap S.aureus sebesar 12,5 mm

Durian leaf (Zibethinus folium) is part of the plant that has antibacterial activity. The purpose of this study was to determine the antibacterial activity of Zibethinusfoliumfraction against Escherichia coliATCC 25922 in vitro. The research method used is experimental. Leaf samples were extracted using maceration method with 70% ethanol and purified by fractionation methods using aqua distilled, n-hexane, and ethyl acetate. Positive controlisclindamycin gel and negative controlis5% DMSO. Statistical analysis was performed with One-Way Anova. Phytochemical screening results show that macerateZibethinus folium contains flavonoids, tannins, saponins and steroids. The test results of antibacterial activity aqua distilled fraction and ethyl acetate fraction of macerateZibethinus foliumshows antibacterial activity against Escherichia coliATCC 25922, while the n-hexane fraction of macerateZibethinus foliumshowed no antibacterial activity against Escherichia coliATCC 25922. aqua distilled fraction of 40% showed a response the most well barriers with zone of inhibition 8.33 ± 0.76 mm, meaning that aqua distilled fraction of 40%  including medium category.

Penyakit menular & Virus corona

Cacao are a plantation commodity in Indonesia. Most of the cacao plant is cacao leaves. One of the utilization of cacao leaves by the community is as compost, but has not been utilized by the community as a raw material of traditional medicine. Based on research, cacao leaves contain secondary metabolite compounds that can be used as an antibacterial against Staphylococcus aureus bacteria that often cause infection in humans. The purpose of this study was to find out the activity of ethanol fraction, dichloromethane, and n-hexane from cacao leaf extract as an antibacterial against Staphylococcus aureus ATCC 25923. This study used extraction methods of maceration and fractionation using ethanol solvents, dichloromethane, and n-hexane. Test the antibacterial activity of cacao leaf fraction using disc diffusion method with a concentration series of 10%, 20%, and 30%. The results showed that ethanol and dichloromethane fractions had antibacterial activity.

This research aims to determine the effect of several doses of liquid organic fertilizer of tomatoes on the growth of cocoa nurseries. Cocoa nurseries need nutrients that support the growth of cocoa seedlings. Liquid organic fertilizer of tomatoes contains the nutrients needed for the growth of cocoa seedlings. This research method was carried out experimentally with 6 treatments of POC doses of a mixture of tomato extract, coconut water, and rice water, with 4 replications. he results of the study, it was explained that giving a dose of 25 ml of POC mixed with tomato extract, coconut water and ricE water/ 100 ml of water had a good effect on the growth and development of cocoa seedlings for the character of seedling height, number of leaves and leaf length. Furthermore, for the character of stem diameter, no significant effect was seen on the increased in stem diameter of cocoa seedlings. To overcome this, it is necessary to increased the dose of fertilizer or add other organic materials that can increases the diameter of the cacao seedlings.