Stereoselective Synthesis of cis-and trans-3,4,5-Trisubstituted-1,3-oxazolidin--2-one Derivatives from 1,2-Amino Alcohol Monoesters and Aziridine-2-carboxylates. -New cis N-alkyl-1,3-oxazolidin-2-ones (III) are formed in good yields via phosgenation of erythro-1,2-aminoalcohol monoesters, accompanied by the formation of aziridine by-products. On the other hand, their regioisomer trans-forms (VI) are build regio-and stereoselectively by ring expansion of trans-N-alkyl aziridine-2-carboxylates (IV). -(KAABI, A.; BESBES*, R.; Synth. Commun. 45 (2015) 1, 111-118, http://dx.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.