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Nutritional incidences of thermooxidised sunflower oil ingestion on serum lipid fractions and on α-tocopherol in growing rats.In the object to determine the nutritional impact on serum lipid fractions in growing rats, we have heated this oil at temperature 98 ± 2˚C with air insufflation and a continue shaking. After 42 hours of heats, this oil presents an acid index near 1.68% peroxide index over 386.3 meq O 2 / kg with 18:2 n-6 content of 38.2% and 30% of polar compounds.This oil has been incorporated to semi-synthetic diet at respectively 5 and 10% doses for nourishing weaning young male rats. A group of rats received 10% of oxidised oil enriched with vitamin E.Treatment duration was about 9 weeks. The results show growth retardation with weight loss and liver hypertrophy in rats having ingested treated oil, low cholesterol, triglyceride and phospholipide concentrations in all treated groups. Diminution of serum cholesterol lipoproteins HDL, LDL and VLDL particularly in rats fed on 5% of oxidised oil against a significant rise (P<0.05) of LDL cholesterol in rats ingested 10% of treated oil. Apo AI are positively correlated to HDL. Both Lp(a) and Apo B are positively correlated with LDL.The effect of period and type of treatment have together a marked influence on all the experimental groups. Furthermore, the effect of dose has a real impact for all parameters studied respectively for the first group which fed on 5 and for the second which fed on 10% of oxidised oil. Moreover, the rats fed 10% of oxidised oil enriched with vitamin E presents a tendency to a re-establishment of different parameters studied above.

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