In a model of stroke in nonhuman primates, HNSCs can survive up to 105 days when transplanted 1 week after an ischemic event and can partly undergo neuronal differentiation.

Highlights d Neuronal selectivity for spatial frequency in area MT changes with stimulus contrast d Preferred spatial frequency changes more at low than at high temporal frequency d Stimulus selectivity depends on excitation-inhibition balance in cortical circuits d The concept of stimulus selectivity as a stable property of neurons needs revision

By comparison with control animals, abcr-/- mice exhibit faster rod recovery after a bleach of approximately 0.03. The data suggest that ABCR in normal rods may directly or indirectly prolong all-trans retinal clearance from the disc lumen over a significant bleaching range, and that the essential function of ABCR may be to promote the clearance of residual amounts of all-trans retinal that remain in the discs long after bleaching.