Hemorrhagic manifestations during COVID-19 infections are increasingly described in the literature. We report the first case of spontaneous subcapsular hematoma of the liver revealing a COVID-19 infection in a 44-year-old woman with no underlying health condition history, a computerized tomography evaluation showed an aspect of lung ground-glass opacities, with moderate impairment estimated at about 20%. Reverse transcription-polymerase chain reaction confirmed the diagnosis of COVID-19 infection. During the COVID-19 pandemic, non-traumatic bleeding such as spontaneous hematomas in patients with no coagulation disorder could be a manifestation of COVID-19 infection.

Hemorrhagic manifestations during COVID-19 infections are increasingly described in the literature. We report the first case of spontaneous sub-capsular hematoma of the liver revealing a COVID-19 infection in a 44-year-old woman with no underlying health condition history, a CT-scan evaluation showed an aspect of lung ground-glass opacities, with moderate impairment estimated about 20%. RT-PCR confirmed the diagnosis of COVID-19 infection. During the epidemic period, it seems necessary to suspect COVID-19 infections in case of spontaneous sub-capsular hematoma of the liver in patients with no trauma story nor coagulation disorder.