In this study, the efficacy of water extracts of rotundus Cyperus tubers was tested. Polium Teucrium and Farcta Prosopis were evaluated in reducing levels glucose, cholesterol and triglycerides in the blood of healthy male rats with diabetes and compared with the effect of insulin. The water extracts of alfalfa, cactus and krub proved to be efficient in lowering the level of glucose in healthy rats and diabetes. As the results demonstrates, the water extract is Thyme tubers caused a significant reduction in the level of cholesterol and triglycerides, while the extract hydrolysis of carob fruits has significantly reduced the level of thalassyl clycerides only, while the water extract did not change for the ventricular fractures of the level of cholesterol and triglycerides in the diabetic rats.