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Objective: Monitor the ameliorative impact of Nigella sativa on fasting blood glucose and serum testosteronelevels in polycystic ovarian syndrome caused by letrozole in mice. Study Design: Laboratory based randomized control trial. Place and Duration of Study: Anatomy department, Army Medical College in teamwork with National Instituteof Health. Time span is Dec 2014 Dec 2015. Methodology: Total 40 mature female BALB/c mice were chosen and distributed in four groups (ten mice in each one). Group 1 was given normal diet. Rests of three groups were treated with Letrozole at dose of 1 mg/kg body weight once daily for eight weeks. Group 3 was also given Nigella sativa seeds powder at dose of 10 g/kg body weight once daily starting at 22 day and continued up to eight weeks. Group 4 was treated with Nigella sativa oil at a dose of 4 ml/kg body weight once daily starting at 22 day and continued up to eight weeks. At termination of trial, fasting blood glucose level (FBG) was recorded by taking blood sample by glucometer from mouse lateral tail vein after 12 hours fasting. Mice with blood glucose level 250-464 mg/dl were marked hyperglycemic. Final blood sample was taken through cardiac puncture for serum testosterone evaluation. Results: Fasting blood glucose and Serum testosterone levels were raised in group 2 animals in comparison togroup 1 while they were reduced remarkably in group 3 and 4 in comparison of group 2. Conclusion: Nigella sativa seeds in both solid and liquid state leave..................

Background: Polycystic ovary syndrome (PCOS) influences almost 18% of women in their child bearing age and responsible for reproductive, metabolic and psychological dysfunctions. Aim: To examine remedial effect of Nigella sativa on body weight, weight, volume and gross appearance of ovary in polycystic ovarian syndrome induced by Letrozole in mice. Study Design: Randomized control trial. Methodology: Mature female BALB/c mice (n=40) were placed in four groups having ten in each. Group-1 was fed with normal diet. Rests of three were treated with Letrozole at dose of 1mg/kg body weight once daily for eight weeks. Groups (3&4) were also given Nigella sativa seeds powder and oil at dose of l0g/kg body weight and 4ml/kg body weight respectively, once daily commencing at 23 day and remained at end of eight weeks. Ovaries were identified, shape and color were recorded then weighed using a digital precision balance and volume in mm3 by water displacement method. Statistical analysis: Data analyzed by SPSS 21.0v. Results: Body weight of group-2 animals, weight and volume of their ovaries was increased in comparison to group-1 but reduced to group-3 and group-4 animals. Blackish spots on group-2 animal ovaries were observed. Ovaries of groups (3&4) animals were normal in appearance, volume and weight Conclusion: This study concluded that Nigella Sativa seeds in both solid and liquid state leave identical curative impact on body weight, weight, volume and gross appearance of ovaries in polycystic ovarian syndrome in mice. Keywords: Body Weight, Letrozole, Nigella Sativa, Ovaries and Polycystic Ovarian Syndrome

Objective: This study is aimed to see level of satisfaction among patients coming to hospital, to identify the problem areas and also towards developing suggestions for better patient care. Methodology: Study design is cross sectional. Hundred indoor and hundred outdoor patients were selected for a period of about 2 months. Data was collected and analyzed by using statistical software SPSS 20. Results: A total of 200 patients were selected in this study,100 indoor patients and 100 outdoor patients. Of these 200 patients, 102 (51%) were male patients while 98 (49%) were female patients. Mean age of our study cases was 39.08 ± 15.33 years, 110 (55%) were from rural areas while 90 (45%) were from urban areas, 129 (64.5%) were literate and 105 (52.5%) were satisfied from the quality of the services being provided. Among indoor patients most unsatisfying point was behavior of nursing staff and among out door patients most unsatisfying point was long waiting time.