This study was conducted to summarize the results of studies investigating the role of neutrophil to lymphocyte ratio (NLR) in epilepsy. The search was conducted on PubMed, Scopus, and Web of Science up to December 25, 2021. Finally, a total of seven studies were included in the review. The NLR in patients who were in the acute phase was higher than that of healthy. NLR in the patients who were in either acute or subacute phase was higher than in healthy controls. A significant difference in NLR levels between the acute and subacute phases was also noted. Epilepsy is one of the most important neurological diseases in the world, and millions of people around the world suffer from it, and a cheap and fast biomarker is needed for it. The interesting thing is that inflammation plays a role in epilepsy, and elevated NLR value can be a good biomarker of inflammation and, as a result, for epilepsy.

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Background. A stapedectomy or stapedotomy is known as the best treatment option for patients with otosclerosis. Otosclerosis is a primary disease of the bony labyrinth capsule, which is characterized by one or more localized foci, where bone deposition occurs repeatedly. The best and most effective treatment option is a stapedectomy or stapedotomy. Objectives. The present study evaluated the short-term hearing results in patients with otosclerosis after primary stapes surgery. Material and methods. in this retrospective study, the short-term hearing results of all patients with otosclerosis after a primary stapedotomy admitted to the Ahvaz Emam hospital from 2007 to 2017 was evaluated. improvement in hearing was evaluated according to the pre-and post-audiometry results. Air conduction (Ac), Bone conduction (Bc) and Air-Bone Gap (ABG) thresholds were recorded at 500, 1 000, 2 000 and 4 000 Hz. SPSS software (Version 22.0) was used for statistical analysis. Results. Of the 413 cases, 231 (55.93%) and 182 (44.07%) were females and males, respectively. The mean age of patients was 39.06 ± 11.29 years. The disease in 131 (31.72%) was bilateral. The mean ABG in 341 patients (82.63%) ≤ 10 dB and in 52 patients (12.47%) was 10-20 dB. Conclusions. The results of the study showed that a primary stapedotomy is a successful and effective way to improve short-term hearing results in adults with otosclerosis.

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