Purpose The purpose of this paper is to investigate the impact of knowledge-based dynamic process capabilities (KBDPCs) on innovation performance, considering the mediator role of innovation processes in the Iranian knowledge-based high-tech companies. Design/methodology/approach Based on an in-depth review of previous studies, the indicators pertaining to the research constructs were extracted. Then, exploratory and confirmatory factor analyses were applied to identify and confirm the research constructs. Partial least squares-based structural equation modeling was used to investigate the intended relationships. Findings The results of the direct effect showed that KBDPCs have a significant positive effect on innovation performance. Further, moderation analysis demonstrated that innovation processes are moderated by the relationship between KBDPCs and innovation performance. Accordingly, the findings revealed that KBDPCs affect product innovation performance and exploratory innovation and transitional innovation increase this effect. Also, the mediator role of exploitation innovation in the relationship between KBDPCs and process innovation performance was proved. Research limitations/implications As this research was performed in the Iranian context, caution should be taken regarding the generalizability of the findings. Practical implications This paper provides a roadmap based on existing scenarios to enhance innovation performance for the surveyed-companies, in particular, and other companies, in general. Social implications The social implication of this study is to respond to the challenge of the managers of Iranian knowledge-based high-tech companies to improve innovation performance through KBDPCs and innovation processes and to grow and develop a sustainable business. Originality/value Given rare studies that have so far been conducted on the research field, this study extends the theories of KBDPCs, innovation processes and innovation performance. The constructs of the research model and relationships intended among them are also significant.