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There are two types of cell death, one is accidental cell death (ACD) and the other is regulated cell death (RCD). ACD is a biologically uncontrollable process caused by disease, while RCD includes welltuned and structured signalling cascades defined as effective molecular mechanisms (Tang et al., 2019). The scientific observation in RCD research started when researchers introduced and defined the terms apoptosis, autophagy, necroptosis, ferroptosis and pyroptosis. Cell death may occur in response to oxidative stress, which activates signalling pathways in multiple forms and can therefore contribute to human diseases such as cancer, tissue damage, autoimmune and inflammatory diseases (Tang et al., 2019). Apoptosis can activate caspase nucleus oligo DNA fragmentation eventually

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