To address the gap in knowledge by providing data and analyses of the status of awareness among Saudi adults. Methods: This cross-sectional questionnaire-based study was carried out in Saudi Arabia from August 2018 to August 2019 through social media platforms using SurveyMonkey. The domains of the questionnaire included demographic information, knowledge of types and symptoms of head and neck cancers)HNCs(, and the relation of HNCs to human papillomavirus)HPV(and its vaccine. Results: A total of 3171 respondents completed the questionnaire. The analysis revealed that many of the study respondents)49.3%(were not knowledgeable about HNCs. Almost two-thirds)61.2%(of the study population incorrectly believed that brain Original Article cancer was included in HNCs. Over half)57.8%(did not recognize headaches as a symptom. In terms of the risk factors, males showed higher awareness of tobacco and excessive alcohol as risk factors, while females were more knowledgeable about HPV infection)p<0.05(. Conclusion: This study revealed that there is a lack of knowledge and awareness of the clinical features of and risk factors for HNCs among the Saudi population.
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