Background: Tissue adhesives are often used in myringoplasty because they can hold the graft in place and help the graft absorb by acting as a framework. Aim of the study: The goal is to look at the temporalis fascia graft used in myringoplasty with and without cyanoacrylate glue and compare the two. Patients, and methods: Fifty patients with dry central tympanic membrane perforation were treated with type I tympanoplasty over the course of 1.5 years. In each instance, the autogenous temporalis fascia graft was spot welded and fixed to flaps and the surrounding tissue using glue. Myringoplasty was done on 50 people, and they were randomly put into two groups: those who had cyanoacrylate glue put on the temporalis fascia graft and those who didn't. Results: Each group had 25 cases, and there were no big differences between the groups in terms of age, direction, or size of the tympanic membrane hole. After 6 weeks, there wasn't much difference between the glue group and the control group. In the glue group, 72% had healed and 28% had perforated, while in the control group, 64% had healed and 36% had perforated (p-value 0.544).

Background: Myringoplasty surgery, also known as tympanic membrane repair, is performed to correct hearing loss brought on by TM perforation and to eliminate recurrent ear discharge. Platelets are the primary players in the process of tissue healing. They provide essential growth factors that stimulate fibroblasts to produce new blood vessels and lay down extracellular matrix. The study aim: Is to assess the efficacy of incorporating plateletrichplasma into tragal cartilage grafts with its perichondrium in order to speed healing and enhance the results of endoscopic transcanalmyringoplasty. Patients, and methods: Fifty people suffer from dry central TM perforation participated in this prospective case-control study. Under local anaesthesia, each of them had endoscopic transcanal myringoplasty by using tragal perichondrium grafts. 25 patients underwent myringoplasty surgery and also received platelet-richplasma (PRP) from the same patient in group A, compared to 25 patients in group B who underwent myringoplasty surgery but did not get PRP. Results: There were 25 patients in each group, and no statistically significant demographic differences existed between the two groups. A p-value of (0.01) indicates that there was a significant difference between the plattelet-rich plasma group's (100%) and the non-plattelet-rich plasma group's (72%) graft absorption success rates.