Apsmar denotes epilepsy, that usually persists in majority of patients with mental debility and disability, in spite of multidrug therapy with advanced anti-epileptics. But by supplementing Sodium valproate with indigenous composite of some Indian herbs as an adjuvant at 8 hourly dosing, tends to modulate the therapeutic outcome positively due to bioregulation of altered GABA bio kinetics and neurogenic action. Thus this adjunction seems a boon in epilepsy management.

No abstract

Cholelithiasis in female is increasing rampantly among obese [1,2], hyperlipidemic and hypo functioning thyroid women who undergone tube ligation or hysterectomy may be synergized by increasing toxic non nutrients in diet and changed life style, Common surgical preference Cholecystectomy and Choledochotomy though relieve the agonizing pain but alter digestion permanently which predisposes for the continuance of the presentation like heaviness in the abdomen, heart burn, eructation, lethargy, bowel irregularity in spite of dietary restriction.Placebo based control study to evaluate a herb mineral composit in 216 cases affirm its worth in relieving clinical presentation and USG confirmation in majority cases with grade I clinical response while control group shows only transient symptomatic relief. 3 years post therapy follow up and dietary restriction with maintenance dose of 1 pill daily, none had any bowel irregularity or any evident cholelithiasis or hyperlipidemia.

Filarial lymphedema, an agonizing presentation of Filariasis, un common

Lactose intolerance diarrhoea and increasing threat of Organo toxicity due to increasing non dietary constituents in the food and drinks, even contamination of milk poses problems in diarrhoea management in spite of big antidiarrheal armamentarium. In addition for the sake of convenience even injudicious combination of potent antimicrobials and antiprotozoal being used inspite of FDA warnings .Thus in the context the present study to evaluate the sugar free Norfloxacin and Sugar free Tinidazole suspension administered separately in therapeutic dose proves worth as compared to sugar based norfloxacin and Tinidazole suspension separately or in combination as Sugar free Tinidazole and Sugar free Norfloxacin administered separately every 12 hours achieves remission without any untoward effects ,drug related toxicity ,relapse ,recurrence and post therapeutic sequel even in neonates .