Eighty nine children with fever which lasted 2 to 30 days were studied. Among them there were 60 patients with demonstrated salmonella typhi or paratyphi infections by blood and or bone marrow cultures; 17 patients were under the school age (PSA) and 43 at school age groups (SA). Bone marrow cell counts, as well as routine hematologicat studies were undertaken in all patients and separately analysed in those with salmonellae infections; Significant evidence of anemia was found in 76% of PSA and 60% SA patients, but it was no longer present in controls done 15 days after the end of the treatment of their infection with Chloramphenicol. Neutropenia, in proportion to the total number of white blood cells, was found in 47% of PSA patients. The absolute number of neutrophils was also reduced in 14%of SA childrea Neutropenia was more severe at the end of treatment and lasted more than 15 days in about one half of all patients. Only 25%of our patients showed increased numbers of band forms in the initial diferential leucocyte counts. Aneosinophilia was found in 83%of PSA and 98%of SA patients. Low platelet counts occurred in 22% of PSA and 42%of SA children, in most of them theie were no abnormalities in their coagulation tests. Normal megalcariocytes and platelet production were noted at the bone marrow microscopic examination, together with erithroid hypoplasia and hyperplasia of granulocytic, monocytic and histiocytic series. Histiocytes frecuently showed evidence of hemophagia of other cellular elements, including platelets, erithrocytcs, erithoblasts, leucocytes and plasma cells.
We re -jrt 47 patients with Schonlein-Henoch syndrome seen by us in the last 5 years. The diagnosis was made on clinicals grounds. The group's means age was 8 years. Sex rates were identical. In 60%of the patients the onset of the syndrome occurred at spring and fall months and also in 60% there were the antecedents that suggested a precedent infectious disease. The mean duration of the clinical manifestation was 14 days (7 to 28 days). Abdominal and articular symptoms occurred in 60% and 40% of the patients respectively and preceded the cutaneous manifestations in 40%of the cases. Evidence of renal compromise was observed in 19%of the cases, but no patients showed deterioration of their renal function during follow-up. Muscular manifestations occurred in 3 patients and one case showed neurological symptoms. Oral steroids were effective in the treatment of severe abdominal pain and were given for no less than seven days. (Keywords: Schonlein-Henoch syndrome, symptoms, signs, laboratory abnormalities).EJ smdrome de Schonlein-Henoch (S. S-H) es una enfermedad multisistemica caracterizada por vasculitis leucocitoclastica 1 -2 con expresion cutanea, articular, gastrointestinal y renal. En ocasiones el diagnostico es dificil y cuando existe compromise abdominal puede simular enfermedades abdominales de tratamiento quirurgico. Con el fin de reconocer las complicaciones y su manejo se analizan los casos de S. S-Hingresados al servicio en los ultimos 5 afios. MATERIAL Y METODOSS; estudiaron 47 pacientes que ingresan al servicio de pediatria del hospital Sotero del Ri'o de Santiago, entre los meses de enero 1980 y marzo 1985, con diagnostico de S. S-H realizado en bases clfnicas, considerando las lesiones cutaneas maculo-papulares en las extremidades inferiores corno elemcntos esenciales. Se registro edad, sexo, epoca del ano, factores desencadenantes, forma de presentation, complicaciones y tratamiento. En todos los pacientes se realize hemograma con recuento de plaquetas, velocidad (horaria) de sedimentation globular, examen de orina completo; en algunos se midio concentration de C^ e Ig A en el suero. Solo se incluye- RESULTADOSVeinticuatro pacientes eran varones. La edad promedio en el momento del diagnostico era 8 anos (rango 3 a 15 anos). La enfermedad ocurrio preferentemente en los meses de otono (36%) y primavera (26%).En 63% de los pacientes exist fan antecedentes morbidos recicntes, sintomas respiratorios (38%); faringoamigdalitis (13%); fiebre tifoidea (4%); estomatitis herpetica (2%), sinusitis (2%) y picadura de insecto (2%); no exist/an antecedentes en 37%. Todos los pacientes tuvieron lesiones cutaneas, siendo estas el requisito fundamental para el diagnostico. Sintomas abdominales se registraron en 30 pacientes (64%), articulares en 20 (43%), renales en 9 (19%), musculares en 3 (6%) y neurologicos en 1 (2%). La duracion de las manifestaciones clinicas fue, en promedio, 14 dias (rango 7 a 28 di'as). Las lesiones cutaneas (47/47 pacientes) consistieron en maculo-papulas confluentes, dolorosas al tacto. La...
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