levels were positive in their second-look. 70% of patients with residual tumors having the greatest diameter less than or equal to 2 cm had normal CA125 with a mean value of 21 u/ml. 42% of patients with tumors having the greatest diameter greater than 2 cm had normal CA125, while all the 8 patients with no macroscopic tumor during surgery had normal CA125 level. These results show that the residual tumor size found in the second-look was related to the serum CA125 level. Conclusion As CA125 levels within normal limits gave more false negatives, the necessity of second-look surgery can not be judged by serum CA125 assay though elevated CA125 levels do predict the presence of tumor.
Introduction/Background* Minimal invasive surgery for interval debulking surgery for stage IV ovarian cancer -52 years old -CT&MRI -11 cm adnexal mass and peritoneal carcinomatosis -PET scan: -Left pleural effusion. -Increased pleural FDG uptake -Giant hypermetabolic adnexal mass Methodology Video recorded surgery Result(s)* Optimal cytorreduction after 3 cycles of chemotherapy. Conclusion* Minimally invasive surgery may be considered for the management of patients with advanced ovarian cancer who have undergone neoadjuvant chemotherapy
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.