The goal of our research was to determine the frequency of oral manifestations among the new revealed HIV-infected persons in 2016. For this we studied the database of the AIDS Center and we explored a certain group of patients with oral manifestations and carried out according to the dental examination. The results are: In 2016 totally were found out 719 new cases of HIV infections in a various stages: 11 (1,53%±8,02%) were Acute stage,130 (18.08%±2.12%) -Asymptomatic stage, 361 (50,21%±0.996%) – Symptomatic Non-AIDS, 214 (29,76%±1.54%) –AIDS, just 3 (0,42%15,4%) – NonAIDS/unknown state. Among of them HIV-associated oral manifestations were found in 245 (34.07%1.39%) patients. We investigated 125 (51,02%0,97%) cases and as a result: 69 (55.2%0.9%) were oral candidiasis, 37 25,52%1,71%)manifestati ons were caused by herpes-vi rus. 9 (6,21%±3,89%) of them were oral hairy leukoplakia, 8 (5,52%±4,13%) - gingivitis and periodontitis, Non Hodgkin’s lymphoma - just 1 (0,14%±26,7%) case and Kaposi’s Sarcoma also 1 (0,14%±26,7%) in the year.