Full-facial volume restoration was well sustained over 18 months with high patient satisfaction and good tolerability.

Ao meu marido Carlos, pela presença constante, pelo imenso amor e apoio em todos os momentos e, mesmo sem perceber, é o grande orientador da minha vida e profissão. Aos meus pais, Miguel e Lucília, pelo exemplo de vida, sempre com amor e sabedoria, iluminando meus passos. À minha irmã Ana Maria, pelo privilégio de tê-la sempre ao meu lado, auxiliando e incentivando-me em toda a minha vida. À Maria Helena e Iriad (in memoriam), pelo carinho e incentivo. Onde quer que o senhor esteja, sei que está feliz por esta realização.

No abstract

Maturity-onset diabetes of the young (MODY) is a heterogeneous group of monogenic forms of diabetes mellitus with distinct clinical features. Clinical dermatological phenotypes in MODY patients are very rare in literature. This report describes a patient with HNF1A-MODY presenting with necrobiosis lipoidica (NL) and granuloma annulare (GA). A 39-year-old asymptomatic woman, with atypical diabetes diagnosed at age 17, has a confirmed HNF1A mutation on exon 2 (c.392G>A, p.R131Q), classified as Pathogenic by the ACMG guidelines. She has reasonable metabolic control using oral anti-diabetic medications and has no chronic diabetic complications. Clinical and histologic diagnoses of both NL and GA were made. We discuss these conditions and their association with MODY.

No abstract