This literature review mainly deals with the concepts of food science,food allergy,allergenomics,bioinformatics and its application in solving challenges pertaining to food allergy.When an after eating a certain food, the immune system gives out a reaction,it is defined as Food Allergy.It is a complex disease that has many challenging area related to its cure and is a worldwide problem. Bioinformatics help in providing solutions to these challenges. As allergens are mainly proteins.There are many allergy databases and tools available in the market that can be used to identify the differences between novel proteins and food allergens that could be the epicentre of multiple allergy syndromes.This review article talks about food allergenicity,allergy and computational approaches employed to solves issues related to it.