Background: To evaluate and compare diagnostic accuracy of modified Alvarado score and ultrasonography in co-relation to histopathology report for diagnosis of acute appendicitis.Methods: A prospective study of the patients who underwent appendectomy for suspected acute appendicitis at IIMS and R Medical College and Noor Hospital Warudi, Badnapur, Dist. Jalna (Maharashtra). The clinical (radiological) and ultrasonography data of 760 patients with suspected appendicitis was collected between March 2014 to Feb. 2017. These patients were evaluated by modified Alvarado score and ultrasonographically, which was corrected with histopathological finding.Results: Out of 760 patients 69.34% had acute appendicitis 63.81% had modified Alvarado score≥7 and 58.28% patients were ultrasonographically positive. In present study modified Alvarado score has sensitivity of 89.37% specificity 93.99% positive predictive value 97.11%, negative predictive value 79.64%, diagnostic accuracy of 81.32%.Conclusions: Modified Alvarado score can be used effectively in clinical decision making. When compare with ultrasonography neither one is advantageous. However, additional information provided by ultrasonography improves diagnostic accuracy.

Background: For a thyroid swelling, FNAC is the primary investigation. In most of the lesions, after excision, the Histopathology remains the same, but at times a few surprises do occur when FNAC reported benign lesions are found to be malignant on histopathology. The study aims to find reliability of FNAC in diagnosing Thyroid Lesions.Methods: This prospective study was conducted on 111 patients with thyroid swelling attending IIMSR, Medical College, Jalna during a period of two years. These patients with thyroid lesions were subjected to FNAC and then following the surgery correlated with the histopathology report.Results: Majority of the patients were in the age group of 30-50 years with female predominance. Out of 111 patients studied with FNAC, 1 sample was inadequate. Among remaining 110 cases 99 were benign thyroid lesions, 6 were malignant and 5 were highly suspicious of malignancy. HPE of thyroid specimen confirmed 101 cases as benign and 9 cases as malignant. Case in which inadequate material was obtained on FNAC was not included in study.Conclusions: FNAC is about 98.18 % reliable in diagnosing thyroid lesions. FNAC is easy, reliable and accurate investigation for all thyroid swellings.